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Impact of vesicular glutamate leakage on synaptic transmission at the calyx of Held

KEY POINTS: It is controversial whether glutamate can leak out of vesicles in the nerve terminal. To address this issue, we abolished vesicular glutamate uptake by washing out presynaptic cytosolic glutamate or by blocking vacuolar ATPase activity using bafilomycin A1. In the absence of vesicular gl...

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Bibliographische Detailangaben
Veröffentlicht in:J Physiol
Hauptverfasser: Takami, Chihiro, Eguchi, Kohgaku, Hori, Tetsuya, Takahashi, Tomoyuki
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5309358/
https://ncbi.nlm.nih.gov/pubmed/27801501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP273467
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