Candidate germline polymorphisms of genes belonging to the pathways of four drugs used in osteosarcoma standard chemotherapy associated with risk, survival and toxicity in non-metastatic high-grade osteosarcoma

This study aimed to identify associations between germline polymorphisms and risk of high-grade osteosarcoma (HGOS) development, event-free survival (EFS) and toxicity in HGOS patients treated with neo-adjuvant chemotherapy and surgery. Germline polymorphisms of 31 genes known to be relevant for tra...

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Detalles Bibliográficos
Publicado en:Oncotarget
Main Authors: Hattinger, Claudia M., Biason, Paola, Iacoboni, Erika, Gagno, Sara, Fanelli, Marilù, Tavanti, Elisa, Vella, Serena, Ferrari, Stefano, Roli, Andrea, Roncato, Rossana, Giodini, Luciana, Scotlandi, Katia, Picci, Piero, Toffoli, Giuseppe, Serra, Massimo
Formato: Artigo
Idioma:Inglês
Publicado: Impact Journals LLC 2016
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5308704/
https://ncbi.nlm.nih.gov/pubmed/27566557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11486
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