A bivalent promoter contributes to stress-induced plasticity of CXCR4 in Ewing sarcoma

Tumor heterogeneity is a major impediment to cancer cures. Tumor cell heterogeneity can arise by irreversible genetic mutation, as well as by non-mutational mechanisms, which can be reversibly modulated by the tumor microenvironment and the epigenome. We recently reported that the chemokine receptor...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Krook, Melanie A., Hawkins, Allegra G., Patel, Rajiv M., Lucas, David R., Van Noord, Raelene, Chugh, Rashmi, Lawlor, Elizabeth R.
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2016
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5308690/
https://ncbi.nlm.nih.gov/pubmed/27528222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11240
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