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Stress-induced CXCR4 Promotes Migration and Invasion of Ewing Sarcoma

Ewing sarcoma is the second most common bone cancer in pediatric patients. Although the primary cause of death in Ewing sarcoma is metastasis, the mechanism underlying tumor spread needs to be elucidated. To this end, the role of the CXCR4/SDF-1a chemokine axis as a mediator of Ewing sarcoma metasta...

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Detalhes bibliográficos
Main Authors: Krook, Melanie A., Nicholls, Lauren A., Scannell, Christopher A., Chugh, Rashmi, Thomas, Dafydd G., Lawlor, Elizabeth R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4058379/
https://ncbi.nlm.nih.gov/pubmed/24651452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-13-0668
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