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Ligand dependent restoration of human TLR3 signaling and death in p53 mutant cells

Diversity within the p53 transcriptional network can arise from a matrix of changes that include target response element sequences and p53 expression level variations. We previously found that wild type p53 (WT p53) can regulate expression of most innate immune-related Toll-like-receptor genes (TLRs...

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Publicat a:Oncotarget
Autors principals: Menendez, Daniel, Lowe, Julie M., Snipe, Joyce, Resnick, Michael A.
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5308678/
https://ncbi.nlm.nih.gov/pubmed/27533082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11210
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