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Id4 dependent acetylation restores mutant-p53 transcriptional activity
BACKGROUND: The mechanisms that can restore biological activity of mutant p53 are an area of high interest given that mutant p53 expression is observed in one third of prostate cancer. Here we demonstrate that Id4, an HLH transcriptional regulator and a tumor suppressor, can restore the mutant p53 t...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3866570/ https://ncbi.nlm.nih.gov/pubmed/24330748 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-12-161 |
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