Id4 dependent acetylation restores mutant-p53 transcriptional activity

BACKGROUND: The mechanisms that can restore biological activity of mutant p53 are an area of high interest given that mutant p53 expression is observed in one third of prostate cancer. Here we demonstrate that Id4, an HLH transcriptional regulator and a tumor suppressor, can restore the mutant p53 t...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Knowell, Ashley E, Patel, Divya, Morton, Derrick J, Sharma, Pankaj, Glymph, Shanora, Chaudhary, Jaideep
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2013
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3866570/
https://ncbi.nlm.nih.gov/pubmed/24330748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-12-161
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller