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ID4 regulates transcriptional activity of wild type and mutant p53 via K373 acetylation

Given that mutated p53 (50% of all human cancers) is over-expressed in many cancers, restoration of mutant p53 to its wild type biological function has been sought after as cancer therapy. The conformational flexibility has allowed to restore the normal biological function of mutant p53 by short pep...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Oncotarget
Prif Awduron: Morton, Derrick J, Patel, Divya, Joshi, Jugal, Hunt, Aisha, Knowell, Ashley E, Chaudhary, Jaideep
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Impact Journals LLC 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5356822/
https://ncbi.nlm.nih.gov/pubmed/27911860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13701
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