p53-responsive TLR8 SNP enhances human innate immune response to respiratory syncytial virus

The Toll-like receptor 8 (TLR8) has an important role in innate immune responses to RNA viral infections, including respiratory syncytial virus (RSV). We previously reported that TLR8 expression was increased directly by the tumor suppressor and transcription factor p53 via a single nucleotide polym...

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Detaylı Bibliyografya
Yayımlandı:J Clin Invest
Asıl Yazarlar: Menendez, Daniel, Snipe, Joyce, Marzec, Jacqui, Innes, Cynthia L., Polack, Fernando P., Caballero, Mauricio T., Schurman, Shepherd H., Kleeberger, Steven R., Resnick, Michael A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Clinical Investigation 2019
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6819090/
https://ncbi.nlm.nih.gov/pubmed/31430261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI128626
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