NUMB negatively regulates the epithelial-mesenchymal transition of triple-negative breast cancer by antagonizing Notch signaling

Triple-negative breast cancer (TNBC), an aggressive subtype of breast cancer with higher rates of early relapse and metastasis, is frequently associated with aberrant activation of epithelial-mesenchymal transition (EMT). Nonetheless, how EMT is initiated and regulated during TNBC progression is not...

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Pubblicato in:Oncotarget
Autori principali: Zhang, Jianchao, Shao, Ximing, Sun, Haiyan, Liu, Ke, Ding, Zhihao, Chen, Juntao, Fang, Lijing, Su, Wu, Hong, Yang, Li, Huashun, Li, Hongchang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2016
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5308634/
https://ncbi.nlm.nih.gov/pubmed/27506933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11062
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