Numb regulates vesicular docking for homotypic fusion of early endosomes via membrane recruitment of Mon1b

Numb is an endocytic protein that plays crucial roles in diverse cellular processes such as asymmetric cell division, cell migration and differentiation. However, the molecular mechanism by which Numb regulates endocytic trafficking is poorly understood. Here, we demonstrate that Numb is a docking r...

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Veröffentlicht in:Cell Res
Hauptverfasser: Shao, Ximing, Liu, Yi, Yu, Qian, Ding, Zhihao, Qian, Wenyu, Zhang, Lei, Zhang, Jianchao, Jiang, Nan, Gui, Linfei, Xu, Zhiheng, Hong, Yang, Ma, Yifan, Wei, Yanjie, Liu, Xiaoqing, Jiang, Changan, Zhu, Minyan, Li, Hongchang, Li, Huashun
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4856763/
https://ncbi.nlm.nih.gov/pubmed/26987402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2016.34
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