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The R-SNARE Endobrevin/VAMP-8 Mediates Homotypic Fusion of Early Endosomes and Late Endosomes

Endobrevin/VAMP-8 is an R-SNARE localized to endosomes, but it is unknown in which intracellular fusion step it operates. Using subcellular fractionation and quantitative immunogold electron microscopy, we found that endobrevin/VAMP-8 is present on all membranes known to communicate with early endos...

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Detalhes bibliográficos
Main Authors: Antonin, Wolfram, Holroyd, Claudia, Tikkanen, Ritva, Höning, Stefan, Jahn, Reinhard
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC14992/
https://ncbi.nlm.nih.gov/pubmed/11029036
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