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Hypoxia-responsive ionizable liposome delivery siRNA for glioma therapy
Here, we report the hypoxia-responsive ionizable liposomes to deliver small interference RNA (siRNA) anticancer drugs, which can selectively enhance cellular uptake of the siRNA under hypoxic and low-pH conditions to cure glioma. For this purpose, malate dehydrogenase lipid molecules were synthesize...
Sparad:
I publikationen: | Int J Nanomedicine |
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Huvudupphovsmän: | , , , , , , , , |
Materialtyp: | Artigo |
Språk: | Inglês |
Publicerad: |
Dove Medical Press
2017
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Ämnen: | |
Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5308568/ https://ncbi.nlm.nih.gov/pubmed/28223799 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S125286 |
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