Hypoxia-responsive ionizable liposome delivery siRNA for glioma therapy

Here, we report the hypoxia-responsive ionizable liposomes to deliver small interference RNA (siRNA) anticancer drugs, which can selectively enhance cellular uptake of the siRNA under hypoxic and low-pH conditions to cure glioma. For this purpose, malate dehydrogenase lipid molecules were synthesize...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Int J Nanomedicine
मुख्य लेखकों: Liu, Hong-Mei, Zhang, Ya-Fei, Xie, Yan-Dong, Cai, Yi-Fan, Li, Bai-Yang, Li, Wen, Zeng, Ling-Yu, Li, Yu-Ling, Yu, Ru-Tong
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Dove Medical Press 2017
विषय:
Original Research
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5308568/
https://ncbi.nlm.nih.gov/pubmed/28223799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S125286
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