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Medulloblastoma and ependymoma cells display increased levels of 5-carboxylcytosine and elevated TET1 expression
BACKGROUND: Alteration of DNA methylation (5-methylcytosine, 5mC) patterns represents one of the causes of tumorigenesis and cancer progression. Tet proteins can oxidise 5mC to 5-hydroxymethylcytosine (5hmC), 5-formylcytosine and 5-carboxylcytosine (5caC). Although the roles of these oxidised forms...
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| Опубликовано в: : | Clin Epigenetics |
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| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
BioMed Central
2017
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5307644/ https://ncbi.nlm.nih.gov/pubmed/28228863 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-016-0306-2 |
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