Dynamics of 5-carboxylcytosine during hepatic differentiation: Potential general role for active demethylation by DNA repair in lineage specification

Patterns of DNA methylation (5-methylcytosine, 5mC) are rearranged during differentiation contributing to the regulation of cell type-specific gene expression. TET proteins oxidize 5mC to 5-hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC), and 5-carboxylcytosine (5caC). Both 5fC and 5caC can be...

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Publicado en:Epigenetics
Autores principales: Lewis, Lara C., Lo, Peggy Cho Kiu, Foster, Jeremy M., Dai, Nan, Corrêa, Ivan R., Durczak, Paulina M., Duncan, Gary, Ramsawhook, Ashley, Aithal, Guruprasad Padur, Denning, Chris, Hannan, Nicholas R. F., Ruzov, Alexey
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 2017
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Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5398770/
https://ncbi.nlm.nih.gov/pubmed/28267381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15592294.2017.1292189
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