5-Carboxylcytosine levels are elevated in human breast cancers and gliomas

BACKGROUND: DNA methylation (5-methylcytosine (5mC)) patterns are often altered in cancers. Ten-eleven translocation (Tet) proteins oxidise 5mC to 5-hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC) and 5-carboxylcytosine (5caC). In addition to their presumptive specific biological roles, these o...

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Bibliografiska uppgifter
I publikationen:Clin Epigenetics
Huvudupphovsmän: Eleftheriou, Maria, Pascual, Ana Jimenez, Wheldon, Lee M., Perry, Christina, Abakir, Abdulkadir, Arora, Arvind, Johnson, Andrew D., Auer, Dorothee T., Ellis, Ian O., Madhusudan, Srinivasan, Ruzov, Alexey
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2015
Ämnen:
Short Report
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4546187/
https://ncbi.nlm.nih.gov/pubmed/26300993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-015-0117-x
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