Immunoinhibitory checkpoint deficiency in medium and large vessel vasculitis

Giant cell arteritis (GCA) causes autoimmune inflammation of the aorta and its large branches, resulting in aortic arch syndrome, blindness, and stroke. CD4(+) T cells and macrophages form organized granulomatous lesions in the walls of affected arteries, destroy the tunica media, and induce ischemi...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Zhang, Hui, Watanabe, Ryu, Berry, Gerald J., Vaglio, Augusto, Liao, Yaping Joyce, Warrington, Kenneth J., Goronzy, Jörg J., Weyand, Cornelia M.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2017
Fag:
PNAS Plus
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5307483/
https://ncbi.nlm.nih.gov/pubmed/28115719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1616848114
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker