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Immune checkpoint dysfunction in large and medium vessel vasculitis
Giant cell arteritis (GCA) is a granulomatous vasculitis of the aorta and its medium-sized branch vessels. CD4 T cells, macrophages, and dendritic cells (DCs) build granulomatous infiltrates that injure the vessel wall and elicit a maladaptive response to injury. Pathological consequences include fr...
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| Publicado no: | Am J Physiol Heart Circ Physiol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5451585/ https://ncbi.nlm.nih.gov/pubmed/28314758 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00024.2017 |
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