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Drosophila larvae synthesize the putative oncometabolite L-2-hydroxyglutarate during normal developmental growth

L-2-hydroxyglutarate (L-2HG) has emerged as a putative oncometabolite that is capable of inhibiting enzymes involved in metabolism, chromatin modification, and cell differentiation. However, despite the ability of L-2HG to interfere with a broad range of cellular processes, this molecule is often ch...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
الحاوية / القاعدة:Proc Natl Acad Sci U S A
المؤلفون الرئيسيون: Li, Hongde, Chawla, Geetanjali, Hurlburt, Alexander J., Sterrett, Maria C., Zaslaver, Olga, Cox, James, Karty, Jonathan A., Rosebrock, Adam P., Caudy, Amy A., Tennessen, Jason M.
التنسيق: Artigo
اللغة:Inglês
منشور في: National Academy of Sciences 2017
الموضوعات:
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC5307464/
https://ncbi.nlm.nih.gov/pubmed/28115720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1614102114
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