The oncometabolite L-2-hydroxyglutarate is a common product of dipteran larval development

The oncometabolite L-2-hydroxyglutarate (L-2HG) is considered an abnormal product of central carbon metabolism that is capable of disrupting chromatin architecture, mitochondrial metabolism, and cellular differentiation. Under most circumstances, mammalian tissues readily dispose of this compound, a...

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Detalhes bibliográficos
Publicado no:Insect Biochem Mol Biol
Main Authors: Mahmoudzadeh, Nader H., Fitt, Alexander J., Schwab, Daniel B., Martenis, William E., Nease, Lauren M., Owings, Charity G., Brinkley, Garrett J., Li, Hongde, Karty, Jonathan A., Sudarshan, Sunil, Hardy, Richard W., Moczek, Armin P., Picard, Christine J., Tennessen, Jason M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7704715/
https://ncbi.nlm.nih.gov/pubmed/33157229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ibmb.2020.103493
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