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SIRT2 Reverses 4-Oxononanoyl Lysine Modification on Histones

Post-translational modifications (PTMs) regulate numerous proteins and are important for many biological processes. Lysine 4-oxononanoylation (4-ONylation) is a newly discovered histone PTM that prevents nucleosome assembly under oxidative stress. Whether there are cellular enzymes that remove 4-ONy...

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Podrobná bibliografie
Vydáno v:J Am Chem Soc
Hlavní autoři: Jin, Jing, He, Bin, Zhang, Xiaoyu, Lin, Hening, Wang, Yi
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5305808/
https://ncbi.nlm.nih.gov/pubmed/27610633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b04977
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