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Thiomyristoyl Peptides as Cell-Permeable Sirt6 Inhibitors

Sirtuins regulate a variety of biological pathways and inhibitors of sirtuins have been actively pursued as tool compounds to study sirtuin biology and as potential therapeutics. Here we demonstrate that thiomyristoyl peptides are potent and cell-permeable inhibitors of Sirt6, one of the seven human...

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Autors principals: He, Bin, Hu, Jing, Zhang, Xiaoyu, Lin, Hening
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4161628/
https://ncbi.nlm.nih.gov/pubmed/25163004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c4ob00860j
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