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SIRT2 and lysine fatty acylation regulate the transforming activity of K-Ras4a

Ras proteins play vital roles in numerous biological processes and Ras mutations are found in many human tumors. Understanding how Ras proteins are regulated is important for elucidating cell signaling pathways and identifying new targets for treating human diseases. Here we report that one of the K...

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Enregistré dans:
Détails bibliographiques
Publié dans:eLife
Auteurs principaux: Jing, Hui, Zhang, Xiaoyu, Wisner, Stephanie A, Chen, Xiao, Spiegelman, Nicole A, Linder, Maurine E, Lin, Hening
Format: Artigo
Langue:Inglês
Publié: eLife Sciences Publications, Ltd 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5745086/
https://ncbi.nlm.nih.gov/pubmed/29239724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.32436
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