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Lysine fatty acylation promotes lysosomal targeting of TNF-α
Tumor necrosis factor-α (TNF-α) is a proinflammation cytokine secreted by various cells. Understanding its secretive pathway is important to understand the biological functions of TNF-α and diseases associated with TNF-α. TNF-α is one of the first proteins known be modified by lysine fatty acylation...
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Publicado no: | Sci Rep |
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Principais autores: | , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4832147/ https://ncbi.nlm.nih.gov/pubmed/27079798 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep24371 |
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