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Lysine fatty acylation promotes lysosomal targeting of TNF-α

Tumor necrosis factor-α (TNF-α) is a proinflammation cytokine secreted by various cells. Understanding its secretive pathway is important to understand the biological functions of TNF-α and diseases associated with TNF-α. TNF-α is one of the first proteins known be modified by lysine fatty acylation...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Jiang, Hong, Zhang, Xiaoyu, Lin, Hening
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4832147/
https://ncbi.nlm.nih.gov/pubmed/27079798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep24371
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