Sirt6 regulates TNFα secretion via hydrolysis of long chain fatty acyl lysine

The Sir2 family of enzymes or sirtuins are known as nicotinamide adenine dinucleotide (NAD)-dependent deacetylases(1) and have been implicated in the regulation of transcription, genome stability, metabolism, and lifespan(2, 3). However, four of the seven mammalian sirtuins have very weak deacetylas...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Jiang, Hong, Khan, Saba, Wang, Yi, Charron, Guillaume, He, Bin, Sebastian, Carlos, Du, Jintang, Kim, Ray, Ge, Eva, Mostoslavsky, Raul, Hang, Howard C., Hao, Quan, Lin, Hening
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3635073/
https://ncbi.nlm.nih.gov/pubmed/23552949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12038
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi