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Sirt6 regulates TNFα secretion via hydrolysis of long chain fatty acyl lysine
The Sir2 family of enzymes or sirtuins are known as nicotinamide adenine dinucleotide (NAD)-dependent deacetylases(1) and have been implicated in the regulation of transcription, genome stability, metabolism, and lifespan(2, 3). However, four of the seven mammalian sirtuins have very weak deacetylas...
Tallennettuna:
| Päätekijät: | , , , , , , , , , , , , |
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| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2013
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3635073/ https://ncbi.nlm.nih.gov/pubmed/23552949 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12038 |
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