Crucial Role of Mesangial Cell-derived Connective Tissue Growth Factor in a Mouse Model of Anti-Glomerular Basement Membrane Glomerulonephritis

Connective tissue growth factor (CTGF) coordinates the signaling of growth factors and promotes fibrosis. Neonatal death of systemic CTGF knockout (KO) mice has hampered analysis of CTGF in adult renal diseases. We established 3 types of CTGF conditional KO (cKO) mice to investigate a role and sourc...

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Publicat a:Sci Rep
Autors principals: Toda, Naohiro, Mori, Kiyoshi, Kasahara, Masato, Ishii, Akira, Koga, Kenichi, Ohno, Shoko, Mori, Keita P., Kato, Yukiko, Osaki, Keisuke, Kuwabara, Takashige, Kojima, Katsutoshi, Taura, Daisuke, Sone, Masakatsu, Matsusaka, Taiji, Nakao, Kazuwa, Mukoyama, Masashi, Yanagita, Motoko, Yokoi, Hideki
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5304211/
https://ncbi.nlm.nih.gov/pubmed/28191821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep42114
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