Increase of Total Nephron Albumin Filtration and Reabsorption in Diabetic Nephropathy

The amount of albumin filtered through the glomeruli and reabsorbed at the proximal tubules in normal and in diabetic kidneys is debated. The megalin/cubilin complex mediates protein reabsorption, but genetic knockout of megalin is perinatally lethal. To overcome current technical problems, we gener...

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Veröffentlicht in:J Am Soc Nephrol
Hauptverfasser: Mori, Keita P., Yokoi, Hideki, Kasahara, Masato, Imamaki, Hirotaka, Ishii, Akira, Kuwabara, Takashige, Koga, Kenichi, Kato, Yukiko, Toda, Naohiro, Ohno, Shoko, Kuwahara, Koichiro, Endo, Tomomi, Nakao, Kazuwa, Yanagita, Motoko, Mukoyama, Masashi, Mori, Kiyoshi
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Nephrology 2017
Schlagworte:
Basic Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5198272/
https://ncbi.nlm.nih.gov/pubmed/27382987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2015101168
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