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Mouse DNA polymerase ι lacking the forty-two amino acids encoded by exon-2 is catalytically inactive in vitro

In 2003, we reported that 129-derived strains of mice carry a naturally occurring nonsense mutation at codon 27 of the Poli gene that would produce a polι peptide of just 26 amino acids, rather then the full-length 717 amino acid wild-type polymerase. In support of the genomic analysis, no polι prot...

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Detaylı Bibliyografya
Yayımlandı:DNA Repair (Amst)
Asıl Yazarlar: Frank, Ekaterina G., McDonald, John P., Yang, Wei, Woodgate, Roger
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5303534/
https://ncbi.nlm.nih.gov/pubmed/28077247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2016.12.004
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