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Lysosome-associated membrane glycoprotein 1 predicts fratricide amongst T cell receptor transgenic CD8(+) T cells directed against tumor-associated antigens
AIM: Autologous as well as allogeneic CD8(+) T cells transduced with tumor antigen specific T cell receptors (TCR) may cause significant tumor lysis upon adoptive transfer. Besides unpredictable life-threatening off-target effects, these TCRs may unexpectedly commit fratricide. We hypothesized lysos...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Oncotarget |
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| Κύριοι συγγραφείς: | , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Impact Journals LLC
2016
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5302936/ https://ncbi.nlm.nih.gov/pubmed/27447745 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10647 |
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