An Atlas of Peroxiredoxins Created Using an Active Site Profile-Based Approach to Functionally Relevant Clustering of Proteins

Peroxiredoxins (Prxs or Prdxs) are a large protein superfamily of antioxidant enzymes that rapidly detoxify damaging peroxides and/or affect signal transduction and, thus, have roles in proliferation, differentiation, and apoptosis. Prx superfamily members are widespread across phylogeny and multipl...

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Bibliographic Details
Published in:PLoS Comput Biol
Main Authors: Harper, Angela F., Leuthaeuser, Janelle B., Babbitt, Patricia C., Morris, John H., Ferrin, Thomas E., Poole, Leslie B., Fetrow, Jacquelyn S.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2017
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5302317/
https://ncbi.nlm.nih.gov/pubmed/28187133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005284
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