An approach to functionally relevant clustering of the protein universe: Active site profile‐based clustering of protein structures and sequences

Protein function identification remains a significant problem. Solving this problem at the molecular functional level would allow mechanistic determinant identification—amino acids that distinguish details between functional families within a superfamily. Active site profiling was developed to ident...

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Detalhes bibliográficos
Publicado no:Protein Sci
Main Authors: Knutson, Stacy T., Westwood, Brian M., Leuthaeuser, Janelle B., Turner, Brandon E., Nguyendac, Don, Shea, Gabrielle, Kumar, Kiran, Hayden, Julia D., Harper, Angela F., Brown, Shoshana D., Morris, John H., Ferrin, Thomas E., Babbitt, Patricia C., Fetrow, Jacquelyn S.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5368075/
https://ncbi.nlm.nih.gov/pubmed/28054422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3112
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