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Structural and Electrostatic Asymmetry at the Active Site in Typical and Atypical Peroxiredoxin Dimers

The peroxiredoxins (Prx) are ubiquitous peroxidases involved in important biological processes; however, details of their enzymatic mechanism remain elusive. To probe potential dynamics-function relationships, molecular dynamics simulations and electrostatic calculations were performed on the atypic...

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Detalhes bibliográficos
Main Authors: Salsbury, Freddie R., Yuan, Ye, Knaggs, Michael H., Poole, Leslie B., Fetrow, Jacquelyn S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3383837/
https://ncbi.nlm.nih.gov/pubmed/22401569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp212606k
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