Molecular-level analysis of the serum antibody repertoire in young adults before and after seasonal influenza vaccination

Molecular understanding of serological immunity to influenza has been confounded by the complexity of the polyclonal antibody response in humans. Here we used high-resolution proteomics analysis of immunoglobulin (referred to as Ig-seq) coupled with high-throughput sequencing of transcripts encoding...

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Bibliografiska uppgifter
I publikationen:Nat Med
Huvudupphovsmän: Lee, Jiwon, Boutz, Daniel R, Chromikova, Veronika, Joyce, M Gordon, Vollmers, Christopher, Leung, Kwanyee, Horton, Andrew P, DeKosky, Brandon J, Lee, Chang-Han, Lavinder, Jason J, Murrin, Ellen M, Chrysostomou, Constantine, Hoi, Kam Hon, Tsybovsky, Yaroslav, Thomas, Paul V, Druz, Aliaksandr, Zhang, Baoshan, Zhang, Yi, Wang, Lingshu, Kong, Wing-Pui, Park, Daechan, Popova, Lyubov I, Dekker, Cornelia L, Davis, Mark M, Carter, Chalise E, Ross, Ted M, Ellington, Andrew D, Wilson, Patrick C, Marcotte, Edward M, Mascola, John R, Ippolito, Gregory C, Krammer, Florian, Quake, Stephen R, Kwong, Peter D, Georgiou, George
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2016
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5301914/
https://ncbi.nlm.nih.gov/pubmed/27820605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.4224
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