Molecular-level analysis of the serum antibody repertoire in young adults before and after seasonal influenza vaccination

Molecular understanding of serological immunity to influenza has been confounded by the complexity of the polyclonal antibody response in humans. Here we used high-resolution proteomics analysis of immunoglobulin (referred to as Ig-seq) coupled with high-throughput sequencing of transcripts encoding...

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שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Nat Med
Main Authors: Lee, Jiwon, Boutz, Daniel R, Chromikova, Veronika, Joyce, M Gordon, Vollmers, Christopher, Leung, Kwanyee, Horton, Andrew P, DeKosky, Brandon J, Lee, Chang-Han, Lavinder, Jason J, Murrin, Ellen M, Chrysostomou, Constantine, Hoi, Kam Hon, Tsybovsky, Yaroslav, Thomas, Paul V, Druz, Aliaksandr, Zhang, Baoshan, Zhang, Yi, Wang, Lingshu, Kong, Wing-Pui, Park, Daechan, Popova, Lyubov I, Dekker, Cornelia L, Davis, Mark M, Carter, Chalise E, Ross, Ted M, Ellington, Andrew D, Wilson, Patrick C, Marcotte, Edward M, Mascola, John R, Ippolito, Gregory C, Krammer, Florian, Quake, Stephen R, Kwong, Peter D, Georgiou, George
פורמט: Artigo
שפה:Inglês
יצא לאור: 2016
נושאים:
Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5301914/
https://ncbi.nlm.nih.gov/pubmed/27820605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.4224
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