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Targeting of phage particles towards endothelial cells by antibodies selected through a multi-parameter selection strategy

One of the hallmarks of cancer is sustained angiogenesis. Here, normal endothelial cells are activated, and their formation of new blood vessels leads to continued tumour growth. An improved patient condition is often observed when angiogenesis is prevented or normalized through targeting of these g...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Mandrup, Ole A., Lykkemark, Simon, Kristensen, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5301479/
https://ncbi.nlm.nih.gov/pubmed/28186116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep42230
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