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Targeting of phage particles towards endothelial cells by antibodies selected through a multi-parameter selection strategy

One of the hallmarks of cancer is sustained angiogenesis. Here, normal endothelial cells are activated, and their formation of new blood vessels leads to continued tumour growth. An improved patient condition is often observed when angiogenesis is prevented or normalized through targeting of these g...

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Библиографические подробности
Опубликовано в: :Sci Rep
Главные авторы: Mandrup, Ole A., Lykkemark, Simon, Kristensen, Peter
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2017
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5301479/
https://ncbi.nlm.nih.gov/pubmed/28186116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep42230
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