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Targeting of phage particles towards endothelial cells by antibodies selected through a multi-parameter selection strategy

One of the hallmarks of cancer is sustained angiogenesis. Here, normal endothelial cells are activated, and their formation of new blood vessels leads to continued tumour growth. An improved patient condition is often observed when angiogenesis is prevented or normalized through targeting of these g...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Mandrup, Ole A., Lykkemark, Simon, Kristensen, Peter
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5301479/
https://ncbi.nlm.nih.gov/pubmed/28186116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep42230
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