Canonical hedgehog signalling regulates hepatic stellate cell‐mediated angiogenesis in liver fibrosis

BACKGROUND AND PURPOSE: Hepatic stellate cells (HSCs) are liver‐specific pericytes regulating angiogenesis during liver fibrosis. We aimed to elucidate the mechanisms by which hedgehog signalling regulated HSC angiogenic properties and to validate the therapeutic implications. EXPERIMENTAL APPROACH:...

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Publicado en:Br J Pharmacol
Autores principales: Zhang, Feng, Hao, Meng, Jin, Huanhuan, Yao, Zhen, Lian, Naqi, Wu, Li, Shao, Jiangjuan, Chen, Anping, Zheng, Shizhong
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2017
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Research Papers
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5301045/
https://ncbi.nlm.nih.gov/pubmed/28052321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13701
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