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Canonical hedgehog signalling regulates hepatic stellate cell‐mediated angiogenesis in liver fibrosis

BACKGROUND AND PURPOSE: Hepatic stellate cells (HSCs) are liver‐specific pericytes regulating angiogenesis during liver fibrosis. We aimed to elucidate the mechanisms by which hedgehog signalling regulated HSC angiogenic properties and to validate the therapeutic implications. EXPERIMENTAL APPROACH:...

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Bibliografische gegevens
Gepubliceerd in:Br J Pharmacol
Hoofdauteurs: Zhang, Feng, Hao, Meng, Jin, Huanhuan, Yao, Zhen, Lian, Naqi, Wu, Li, Shao, Jiangjuan, Chen, Anping, Zheng, Shizhong
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5301045/
https://ncbi.nlm.nih.gov/pubmed/28052321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13701
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