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Canonical hedgehog signalling regulates hepatic stellate cell‐mediated angiogenesis in liver fibrosis

BACKGROUND AND PURPOSE: Hepatic stellate cells (HSCs) are liver‐specific pericytes regulating angiogenesis during liver fibrosis. We aimed to elucidate the mechanisms by which hedgehog signalling regulated HSC angiogenic properties and to validate the therapeutic implications. EXPERIMENTAL APPROACH:...

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Publicat a:Br J Pharmacol
Autors principals: Zhang, Feng, Hao, Meng, Jin, Huanhuan, Yao, Zhen, Lian, Naqi, Wu, Li, Shao, Jiangjuan, Chen, Anping, Zheng, Shizhong
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5301045/
https://ncbi.nlm.nih.gov/pubmed/28052321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13701
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