Canonical hedgehog signalling regulates hepatic stellate cell‐mediated angiogenesis in liver fibrosis

BACKGROUND AND PURPOSE: Hepatic stellate cells (HSCs) are liver‐specific pericytes regulating angiogenesis during liver fibrosis. We aimed to elucidate the mechanisms by which hedgehog signalling regulated HSC angiogenic properties and to validate the therapeutic implications. EXPERIMENTAL APPROACH:...

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Veröffentlicht in:Br J Pharmacol
Hauptverfasser: Zhang, Feng, Hao, Meng, Jin, Huanhuan, Yao, Zhen, Lian, Naqi, Wu, Li, Shao, Jiangjuan, Chen, Anping, Zheng, Shizhong
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2017
Schlagworte:
Research Papers
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5301045/
https://ncbi.nlm.nih.gov/pubmed/28052321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13701
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