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Canonical hedgehog signalling regulates hepatic stellate cell‐mediated angiogenesis in liver fibrosis

BACKGROUND AND PURPOSE: Hepatic stellate cells (HSCs) are liver‐specific pericytes regulating angiogenesis during liver fibrosis. We aimed to elucidate the mechanisms by which hedgehog signalling regulated HSC angiogenic properties and to validate the therapeutic implications. EXPERIMENTAL APPROACH:...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Zhang, Feng, Hao, Meng, Jin, Huanhuan, Yao, Zhen, Lian, Naqi, Wu, Li, Shao, Jiangjuan, Chen, Anping, Zheng, Shizhong
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5301045/
https://ncbi.nlm.nih.gov/pubmed/28052321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13701
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