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New CRISPR-Cas systems from uncultivated microbes
CRISPR-Cas systems provide microbes with adaptive immunity by employing short sequences, termed spacers, that guide Cas proteins to cleave foreign DNA(1,2). Class 2 CRISPR-Cas systems are streamlined versions in which a single Cas protein bound to RNA recognizes and cleaves targeted sequences(3,4)....
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| Udgivet i: | Nature |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5300952/ https://ncbi.nlm.nih.gov/pubmed/28005056 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature21059 |
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