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Foreign DNA capture during CRISPR–Cas adaptive immunity
Bacteria and archaea generate adaptive immunity against phages and plasmids by integrating foreign DNA of specific 30–40 base pair (bp) lengths into clustered regularly interspaced short palindromic repeats (CRISPR) loci as spacer segments(1–6). The universally conserved Cas1–Cas2 integrase complex...
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| Udgivet i: | Nature |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4662619/ https://ncbi.nlm.nih.gov/pubmed/26503043 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature15760 |
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