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Mechanism of foreign DNA selection in a bacterial adaptive immune system
In bacterial and archaeal CRISPR immune pathways, DNA sequences from invading bacteriophage or plasmids are integrated into CRISPR loci within the host genome, conferring immunity against subsequent infections. The ribonucleoprotein complex Cascade utilizes RNAs generated from these loci to target c...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3397241/ https://ncbi.nlm.nih.gov/pubmed/22521690 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2012.03.020 |
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