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A scoutRNA is required for some type V CRISPR-Cas systems
CRISPR-Cas12c/d proteins share limited homology with Cas12a and Cas9 bacterial CRISPR RNA (crRNA)-guided nucleases used widely for genome editing and DNA detection. However, Cas12c (C2c3)- and Cas12d (CasY)-catalyzed DNA cleavage and genome editing activities have not been directly observed. We show...
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| Publicado no: | Mol Cell |
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| Principais autores: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8196889/ https://ncbi.nlm.nih.gov/pubmed/32645367 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2020.06.022 |
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