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A thermostable Cas9 with increased lifetime in human plasma
CRISPR-Cas9 is a powerful technology that has enabled genome editing in a wide range of species. However, the currently developed Cas9 homologs all originate from mesophilic bacteria, making them susceptible to degradation and unsuitable for applications requiring cleavage at elevated temperatures....
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| Publicado no: | Nat Commun |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5681539/ https://ncbi.nlm.nih.gov/pubmed/29127284 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01408-4 |
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