Hedgehog signaling in bone regulates whole-body energy metabolism through a bone–adipose endocrine relay mediated by PTHrP and adiponectin

Bone plays a role in energy metabolism, but the interplay between bone and other organs in this process is not completely understood. Here, we show that upregulated Hh signaling in bones results in increased whole-body energy expenditure, white adipose tissue (WAT) browning, hypoglycemia and skeleta...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cell Death Differ
Egile Nagusiak: Zhang, Xu, Cheng, Qianni, Wang, Yixiang, Leung, Po Sing, Mak, Kinglun Kingston
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2017
Gaiak:
Original Paper
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5299706/
https://ncbi.nlm.nih.gov/pubmed/27740628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2016.113
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