Advanced glycation end products induce brain-derived neurotrophic factor release from human platelets through the Src-family kinase activation

BACKGROUND: Brain-derived neurotrophic factor (BDNF) exerts beneficial effects not only on diabetic neuropathies but also on cardiovascular injury. There is argument regarding the levels of serum BDNF in patients with diabetes mellitus (DM). Because BDNF in peripheral blood is rich in platelets, thi...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Cardiovasc Diabetol
Autori principali: Furukawa, Kazuo, Fuse, Ichiro, Iwakura, Yuriko, Sotoyama, Hidekazu, Hanyu, Osamu, Nawa, Hiroyuki, Sone, Hirohito, Takei, Nobuyuki
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2017
Soggetti:
Original Investigation
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5299653/
https://ncbi.nlm.nih.gov/pubmed/28178976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12933-017-0505-y
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