Advanced glycation end products induce brain-derived neurotrophic factor release from human platelets through the Src-family kinase activation

BACKGROUND: Brain-derived neurotrophic factor (BDNF) exerts beneficial effects not only on diabetic neuropathies but also on cardiovascular injury. There is argument regarding the levels of serum BDNF in patients with diabetes mellitus (DM). Because BDNF in peripheral blood is rich in platelets, thi...

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Bibliografski detalji
Izdano u:Cardiovasc Diabetol
Glavni autori: Furukawa, Kazuo, Fuse, Ichiro, Iwakura, Yuriko, Sotoyama, Hidekazu, Hanyu, Osamu, Nawa, Hiroyuki, Sone, Hirohito, Takei, Nobuyuki
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2017
Teme:
Original Investigation
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5299653/
https://ncbi.nlm.nih.gov/pubmed/28178976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12933-017-0505-y
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