Advanced glycation end products induce brain-derived neurotrophic factor release from human platelets through the Src-family kinase activation

BACKGROUND: Brain-derived neurotrophic factor (BDNF) exerts beneficial effects not only on diabetic neuropathies but also on cardiovascular injury. There is argument regarding the levels of serum BDNF in patients with diabetes mellitus (DM). Because BDNF in peripheral blood is rich in platelets, thi...

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Publicado en:Cardiovasc Diabetol
Autores principales: Furukawa, Kazuo, Fuse, Ichiro, Iwakura, Yuriko, Sotoyama, Hidekazu, Hanyu, Osamu, Nawa, Hiroyuki, Sone, Hirohito, Takei, Nobuyuki
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2017
Materias:
Original Investigation
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5299653/
https://ncbi.nlm.nih.gov/pubmed/28178976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12933-017-0505-y
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